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Apirax (Apixaban)

  • Generic name: Apixaban
  • Pharmacologic Category: Anticoagulant
  • Dosage Forms: Tablet, Oral (2.5 mg, 5 mg) 
  • Mechanism of Action: A direct, selective inhibitor of Factor Xa 
  • Reduction of Risk of Stroke and Systemic Embolism in Patients with Nonvalvular Atrial Fibrillation
  • Prophylaxis of Deep Vein Thrombosis Following Hip or Knee Replacement Surgery
  • Treatment of Deep Vein thrombosis
  • Treatment of DVT and PE
  • Reduction in the risk of recurrence of DVT and PE
  • New generation of oral anticoagulants
  • predictable anticoagulation
  • no requirement for routine coagulation monitoring
  • fewer drug-drug interactions
  • No food restrictions or meal requirements
  • no frequent dose adjustment based on age, sex and weight
  • Can be used in patients with end-stage renal disease (ESRD) on dialysis
  • Pregnancy and Breast-Feeding
  • severe hepatic impairment
  • Serious hypersensitivity to Apirax or any component of the formulation
  • Severe and active bleeding
  • Patients who are under 18 years’ old
 

Apirax is a prescription medicine used to:

Apixaban is a selective inhibitor of FXa. Apixaban inhibits free and clot-bound FXa and indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development.
reduce the risk of stroke and blood clots in people who have a medical condition called atrial fibrillation that is not caused by a heart valve problem. With atrial fibrillation, part of the heart does not beat the way it should. This can lead to the formation of blood clots, which can travel to the brain, causing a stroke, or to other parts of the body .
treat blood clots in the veins of your legs (deep vein thrombosis or DVT) or lungs (pulmonary embolism or PE)
reduce the risk of blood clots happening again in people who continue to be at risk for DVT or PE after receiving treatment for blood clots for at least 6 months
help prevent a blood clot in the legs and lungs of people who have just had hip or knee replacement surgery
If you miss a dose of APIRAX, take it as soon as you remember, and do not take more than one dose at the same time.

 

Did you know, if you have AFib not caused by a heart valve problem, you are 5x more likely to have a stroke

It was estimate that in 2020

Would have AFib not Cauesd by a heart valve problem

 

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