Alteplase (ALTELYSE ®)
Pharmacologic Category: Thrombolytics
Dosage Forms: Lyophilized powder (50 mg) with Sterile water for injection
Description:
Alteplase is a recombinant human tissue-type plasminogen activator, which activates plasminogen directly to plasmin leading to the dissolution of the fibrin clot.
Indications:
- Thrombolytic treatment in acute myocardial infraction (AMI) for the reduction of mortality and reduction of the incidence of heart failure
- Thrombolytic treatment in acute massive pulmonary embolism (PE)
- Thrombolytic treatment in acute ischemic stroke
ALTELYSE® is the first biosimilar form of Alteplase in the world
Do you know Alteplase is the only FDA-approved medication indicated for the treatment of acute ischemic stroke?
Do you know, heart failure occurs up to 13% of patients at 30 days and 20–30% of patients at 1 year after MI hospital discharge.