Arena Life Science

Alteplase (ALTELYSE ®)

Generic name: Alteplase

Pharmacologic Category: Thrombolytics

Dosage Forms: Lyophilized powder (50 mg) with Sterile water for injection


Alteplase is a recombinant human tissue-type plasminogen activator, which activates plasminogen directly to plasmin leading to the dissolution of the fibrin clot.


  • Thrombolytic treatment in acute myocardial infraction (AMI) for the reduction of mortality and reduction of the incidence of heart failure
  • Thrombolytic treatment in acute massive pulmonary embolism (PE)
  • Thrombolytic treatment in acute ischemic stroke

ALTELYSE® is the first biosimilar form of Alteplase in the world


Do you know Alteplase is the only FDA-approved medication indicated for the treatment of acute ischemic stroke?

Do you know, heart failure occurs up to 13% of patients at 30 days and 20–30% of patients at 1 year after MI hospital discharge.


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  • Alteplase (Altelyse)
  • Alteplase (Altelyse)
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Company Address

No 20, 5th Floor , 8th Sharestan , Makoueipour St, Za'feraniyeh, Tehran-Iran

Phone: (+98) 21 26 80 5483 - 21 26 80 5489 - Fax: (+98)21 26 80 5478     Email: