Generic name: Ranolazine
Pharmacologic Category: Anti-anginal
Dosage Forms: 500 mg extended-release tablet
Mechanism of Action: A direct, selective inhibitor of Factor Xa
- Treatment of chronic/refractory angina with no effect on heart rate and blood pressure.
Ranolazine acts by inhibiting the cardiac late sodium current (INa) and
hence prevents sodium dependent calcium accumulation in the cell.
It is important to know, 25-30% of patients with coronary artery disease have
persistent angina pectoris despite of PCI with or without optimal medical therapy