Sitagliptin (Diaptin®)

Generic name: Sitagliptin

Pharmacologic Category: Antidiabetic agent

Dosage Forms: Tablet, Oral (50mg, 100 mg)

Description:

• Sitagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor used in conjunction with diet and exercise to improve glycemic control in patients with type 2 diabetes mellitus. The effect of this medication leads to glucose dependent increases in insulin and decreases in glucagon to improve control of blood sugar. Sitagliptin can be taken with or without meal.

Indication:

• Is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.                        
• Diaptin® is produced at a GMP approved manufacturing site

Do you know, in diabetic patients with inadequate glycemic control, addition of sitagliptin to the combination of Metformin and pioglitazone can improve glycemic control without increase in hypoglycemia risk?